Isolation, identification and genomic characterization of the Asian lineage Zika virus imported to China
Fecha
2016-06Autor
Deng, Yong-Qiang
Zhao, Hui
Li, Xiao-Feng
et al.
Metadatos
Mostrar el registro completo del ítemResumen
Zika virus (ZIKV) used to be an unknown mosquito-borne flavivirus, and maintained its limited sylvatic circulation in a few African and Asian countries (Enfissi et al.,
2016). Based on available clinical data, the symptoms in
human infections with ZIKV are supposed to be similar to
other arbovirus infections such as dengue, and characterized
by fever, skin rashes, conjunctivitis, muscle and joint pain,
malaise, and headache (Duffy et al., 2009). However, its
occasional introduction to the Americas resulted in unexpected large outbreaks with millions of human cases since
2015 (Fauci and Morens, 2016). Even worsen, substantial
evidence has linked microcephaly in infants, a severe form
of birth defect, to ZIKV infection in pregnant women
(Mlakar et al., 2016). On 1 February 2016, the World
Health Organization has stated ZIKV and observed increase
in neurological disorders and neonatal malformations a public health emergency of international concern. Now, ZIKV
has rapidly spread to more than 52 countries and territories
in Africa, Americas, Asia and the Pacific.