dc.contributor.author | Monath, T P | |
dc.contributor.author | Schlesinger, J J | |
dc.contributor.author | Brandriss, M W | |
dc.contributor.author | et al. | |
dc.date.accessioned | 2023-01-13T20:25:11Z | |
dc.date.available | 2023-01-13T20:25:11Z | |
dc.date.issued | 2014 | |
dc.identifier.uri | https://pubmed.ncbi.nlm.nih.gov/6206738/ | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.12663/3364 | |
dc.description.abstract | Monoclonal antibodies directed against the envelope glycoprotein and the NV3 non-structural viral protein of yellow fever (YF) were tested by the indirect fluorescent antibody technique against a variety of YF virus strains and heterologous flaviviruses. Monoclonal antibodies directed against the envelope glycoprotein exhibited YF strain-specificity, YF type-specificity, broad group cross-reactivity, or limited subgroup reactivity (YF + Banzi or YF + Koutango + Zika + Usutu + Uganda S). Monoclonal antibodies directed against NV3 reacted either with YF + Koutango or with YF + Banzi. These findings generally correlated with the results of biological tests reported previously. Monoclonal antibodies that were type-specific to YF will be useful for the rapid specific identification of YF virus isolates and are available from the Centers for Disease Control on request. | en_US |
dc.language | English | en_US |
dc.subject | Zika Research Project | en_US |
dc.subject | Zika Virus | en_US |
dc.subject | Yellow Fever | en_US |
dc.subject | Monoclonal Antibodies | en_US |
dc.title | Yellow fever monoclonal antibodies: type-specific and cross-reactive determinants identified by immunofluorescence | en_US |
eihealth.country | Others | en_US |
eihealth.category | Epidemiology and epidemiological studies | en_US |
eihealth.type | Research protocol information | en_US |
eihealth.maincategory | Save Lives / Salvar Vidas | en_US |
dc.relation.ispartofjournal | American Journal of Tropical Medicine and Hygiene | en_US |