ListarTechnical documents and research evidence on COVID-19 por tema "SARS-CoV-2"
Mostrando ítems 1-20 de 180
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Ad hoc laboratory-based surveillance of SARS-CoV-2 by real-time RT-PCR using minipools of RNA prepared from routine respiratory samples
(2020-04-22)Background: A novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in China in late 2019 and subsequently caused a pandemic. Surveillance is important to better appreciate this evolving ... -
Addition of Tocilizumab to the Standard of Care Reduces Mortality in Severe COVID-19: A Systematic Review and Meta-Analysis
(2020-10-02)Introduction: Tocilizumab (TCZ) is an anti-interleukin-6 antibody that has been used for the treatment of severe coronavirus disease 2019 (COVID-19). However, concrete evidence of its benefit in reducing mortality in severe ... -
Advances in SARS-CoV-2: a systematic review
(2020-09-28)OBJECTIVE: In December 2019, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection broke out in Wuhan, China. However, we still lack a comprehensive understanding of this emerging virus. In this manuscript, ... -
Analysis of clinical characteristics and laboratory findings of 95 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a retrospective analysis
(2020-03-26)Background: Since December 2019, 2019 novel coronavirus pneumonia emerged in Wuhan city and rapidly spread throughout China and even the world. We sought to analyse the clinical characteristics and laboratory findings of ... -
Anesthetic Management of Patients Undergoing Aortic Dissection Repair With Suspected Severe Acute Respiratory Syndrome COVID-19 Infection
(2020-03-24)Severe acute respiratory syndrome coronavirus-2 is still active in Wuhan, China, and is spreading to the rest of the world. Recently, perioperative anesthetic management in patients with suspected or confirmed coronavirus-2 ... -
Angiotensin‐converting enzyme‐2 (ACE2 ), SARS‐CoV ‐2 and pathophysiology of coronavirus disease 2019 (COVID ‐19)
(2020-05-17)[Abstract]. Angiotensin‐converting enzyme‐2 (ACE2) has been established as the functional host receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus responsible for the current devastating ... -
Antibody Responses to SARS-CoV-2 in Patients With Novel Coronavirus Disease 2019
(2020-05-28)Background: The novel coronavirus SARS-CoV-2 is a newly emerging virus. The antibody response in infected patients remains largely unknown, and the clinical value of antibody testing has not been fully demonstrated. Methods: ... -
Aptamers, the bivalent agents as probes and therapies for coronavirus infections: A systematic review
(2020-10)Abstract The recently known coronavirus, SARS-CoV-2, has turn into the greatest global health challenge, affecting a large number of societies. The lack of specific treatment and gold-standard diagnostic system has made ... -
Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes
(2020-05-01)Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of blood glucose (BG) control on the degree of required medical interventions and on mortality in patients with COVID-19 and T2D remains uncertain. ... -
Biorisk assessment for infrastructure & biosafety requirements for the laboratories providing coronavirus SARS-CoV-2/(COVID-19) diagnosis
(2020)Novel coronavirus infection [coronavirus disease 2019 (COVID-19)] has spread to more than 203 countries of various regions including Africa, America, Europe, South East Asia and Western Pacific. The WHO had declared COVID-19 ... -
BMJ Best Practice: Management of coexisting conditions in the context of COVID-19. Straight to the point of care
(2020-09-30)This page summarises important considerations for the care of people with co-existing medical conditions during the COVID-19 pandemic. Key points from guidance and position statements are summarised for each condition, and ... -
Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19)
(2020-03-27)Importance: Virus infection has been widely described as one of the most common causes of myocarditis. However, less is known about the cardiac involvement as a complication of severe acute respiratory syndrome coronavirus ... -
Cell-based therapies for COVID-19: A living, systematic review
(2020-12-17)Objective: This living, systematic review aims to provide a timely, rigorous, and continuously updated summary of the available evidence on the role of cell-based therapies in the treatment of patients with COVID-19. Data ... -
Chapter of Gastroenterologists professional guidance on risk mitigation for gastrointestinal endoscopy during COVID-19 pandemic in Singapore
(2020-04-03)[Abstract]. In this paper, we aimed to provide professional guidance to practising gastrointestinal (GI) endoscopists for the safe conduct of GI endoscopy procedures during the current coronavirus disease 2019 (COVID-19) ... -
Characteristics of registered clinical trials assessing treatments for COVID-19: a cross-sectional analysis
(2020-06-09)Objectives The coronavirus disease 2019 (COVID-19) pandemic has prompted many initiatives to identify safe and efficacious treatments, yet little is known regarding where early efforts have focused. We aimed to characterise ... -
Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
(2020-03-27)Since 2002, beta coronaviruses (CoV) have caused three zoonotic outbreaks, SARS-CoV in 2002–2003, MERS-CoV in 2012, and the newly emerged SARS-CoV-2 in late 2019. However, little is currently known about the biology of ... -
Children with Coronavirus Disease 2019 (COVID‐19): A Review of Demographic, Clinical, Laboratory and Imaging Features in 2,597 Pediatric Patients
(2020-05-17)An epidemic of coronavirus disease 2019 (COVID‐19) has been spreading worldwide. With the rapid increase in the number of infections, children with COVID‐19 appear to be rising. Most research findings regarding adult cases, ... -
Chloroquine and hydroxychloroquine: Current evidence for their effectiveness in treating COVID-19
(2020-03-25)Verdict: Several in vitro studies report antiviral activity of chloroquine and hydroxychloroquine against SARS-CoV-2. In vivo data, although promising, is currently limited to one study with considerable limitations. On ... -
The clinical and immunological features of pediatric COVID-19 patients in China
(2020-04-14)In December 2019, the corona virus disease 2019 (COVID-19) caused by novel coronavirus (SARS-CoV-2) emerged in Wuhan, China and rapidly spread worldwide. Few information on clinical features and immunological profile of ... -
Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study
(2020-03-26)Objective: To delineate the clinical characteristics of patients with coronavirus disease 2019 (covid-19) who died. Design: Retrospective case series. Setting: Tongji Hospital in Wuhan, China. Participants: Among a cohort ...