Browsing Technical documents and research evidence on COVID-19 by Subject "SARS-CoV"
Now showing items 1-20 of 88
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Acute Kidney Injury in Hospitalized Patients with COVID-19
(2020-05-08)Importance: Preliminary reports indicate that acute kidney injury (AKI) is common in coronavirus disease (COVID)-19 patients and is associated with worse outcomes. AKI in hospitalized COVID-19 patients in the United States ... -
Anti-hypertensive Angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients
(2020-03-27)Background: The novel coronavirus (CoV) severe acute respiratory syndrome (SARS)-CoV-2 outbreak started at the end of 2019 in Wuhan, China, and spread over 100 countries. SARS-CoV-2 uses the membrane protein Angiotensin I ... -
Assessing the impact of non-pharmaceutical interventions on SARS-CoV-2 transmission in Switzerland
(2020-05-08)Following the rapid dissemination of COVID-19 cases in Switzerland, large-scale non- pharmaceutical interventions (NPIs) were implemented by the cantons and the federal government between February 28 and March 20. Estimates ... -
Assessment tool for laboratories implementing COVID-19 virus testing. Interim guidance, 8 April 2020
(2020-04-08)Background: This tool has been designed to assess the capacity of laboratories that have implemented or intend to implement testing for SARS-CoV-2, the virus that causes novel coronavirus disease 2019 (COVID-19). The tool ... -
Association of Personal Protective Equipment Use with Successful Protection Against COVID-19 Infection Among
(2020-04-28)The coronavirus disease 2019 (COVID-19) pandemic has posed a major challenge for protecting health care workers (HCWs) against the infection. Use of personal protective equipment (PPE) in health care workplace is recommended ... -
Atazanavir inhibits SARS-CoV-2 replication and pro-inflammatory cytokine production
(2020-04-04)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of the ongoing pandemic of 2019 CoV disease (COVID-19), which is already responsible for far more deaths than were reported during the ... -
Breakthrough: Chloroquine Phosphate Has Shown Apparent Efficacy in Treatment of COVID-19 Associated Pneumonia in Clinical Studies
(2020-02-29)The coronavirus disease 2019 (COVID-19) virus is spreading rapidly, and scientists are endeavoring to discover drugs for its efficacious treatment in China. Chloroquine phosphate, an old drug for treatment of malaria, is ... -
Can Nebulised Heparin Reduce Time to Extubation in SARS CoV 2 The CHARTER Study Protocol
(2020-05-12)Introduction: COVID 19 is associated with the development of ARDS displaying the typical features of diffuse alveolar damage with extensive pulmonary coagulation activation resulting in fibrin deposition in the microvasculature ... -
Caution should be exercised for the detection of SARS‐CoV‐2, especially in the elderly
(2020-03-30)In December 2019, a pneumonia outbreak, caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), was first identified in Wuhan, China and presented a major threat to public health. Nationwide, there were ... -
Children account for a small proportion of diagnoses of SARS-CoV-2 5 infection and do not exhibit greater viral loads than adults
(2020-03)[Methods] We analyzed the number of SARS-CoV-2 RNA tests of respiratory samples sent to our 32 laboratory between end of February and mid-March 2020. Clinical symptoms and mortality rate were analyzed among SARS-CoV-2-positive ... -
Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study
(2020-03)Background: We need an effective treatment to cure COVID-19 patients and to decrease virus carriage duration. Methods: We conducted an uncontrolled, non-comparative, observational study in a cohort of 80 relatively mildly ... -
Clinical Characteristics and Short-Term Outcomes of Severe Patients with COVID-19 in Wuhan, China
(2020-04-29)Objective. A novel pneumonia (COVID-19) which is sweeping the globe was started in December, 2019, in Wuhan, China. Most deaths occurred in severe and critically cases, but information on prognostic risk factors for severe ... -
Clinical Characteristics of Children With Coronavirus Disease 2019 in Hubei, China
(2020-03-24)Since December 2019, COVID-19 has occurred unexpectedly and emerged as a health problem worldwide. Despite the rapidly increasing number of cases in subsequent weeks, the clinical characteristics of pediatric cases are ... -
Clinical Performance of SARS-CoV-2 Molecular Testing
(2020-05-08)Molecular testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the gold standard for diagnosis of coronavirus disease 2019 (COVID-19), but the test clinical performance is poorly understood. From ... -
Comparison of two commercial molecular tests and a laboratory-developed modification of the CDC 2019-nCOV RT-PCR assay for the qualitative detection of SARS-CoV-2 from upper respiratory tract specimens
(2020-05-06)We compared the ability of 2 commercial molecular amplification assays [RealTime SARS-CoV-2 on the m2000 (Abbott) and ID NOW™ COVID-19 (Abbott)] and a laboratory developed test [modified CDC 2019-nCoV RT-PCR assay with RNA ... -
Comprehensive Testing Highlights Racial, Ethnic, and Age Disparities in the COVID-19 Outbreak
(2020-05-09)The United States (US), which is currently the epicenter for the COVID-19 pandemic, is a country whose demographic composition differs from that of other highly-impacted countries. US-based descriptions of SARS-CoV-2 ... -
Containing Covid-19 outbreaks with spatiallytargeted short-term lockdowns and mass-testing
(2020-05-09)We assess the efficacy of spatially targeted lockdown or mass-testing and case-isolation in individual communities, as a compliment to contact-tracing and social-distancing, for containing SARS-CoV-2 outbreaks. Using the ... -
Coronavirus Disease (COVID-19): A primer for emergency physicians
(2020-03-24)Introduction. Rapid worldwide spread of Coronavirus Disease 2019 (COVID-19) has resulted in a global pandemic. Objective. This review article provides emergency physicians with an overview of the most current understanding ... -
COVID-19 in healthcare workers in three hospitals in the South of the Netherlands, March 2020
(2020-05-01)Background: Ten days after the first reported case of SARS-CoV-2 infection in the Netherlands, 3.9% of healthcare workers (HCWs) in nine hospitals located in the South of the Netherlands tested positive for SARS-CoV-2 RNA. ... -
COVID-19 in people living with human immunodeficiency virus: A case series of 33 patients
(2020-05-01)Data on people living with human immunodeficiency virus (PLWH) in the current SARS-CoV-2 pandemic is still scarce. This case series of 33 PLWH patients with COVID-19 reveals symptoms and outcome in this special population. ...