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Bacille Calmette-Guérin (BCG) vaccination and COVID-19. Scientific Brief, 12 April 2020
(2020-04-12)Summary: There is no evidence that the Bacille Calmette-Guérin vaccine (BCG) protects people against infection with COVID-19 virus. Two clinical trials addressing this question are underway, and WHO will evaluate the ... -
BCG versus COVID-19: impact on urology
(2020-05-16)Purpose: To search for evidence base for using BCG in the fight against COVID-19 and the possible impact of these clinical trials on urology practice. Methods: A literature review about the basis of the ongoing clinical ... -
Considerations on Thrombotic Events Following Administration of the AstraZeneca COVID-19 Vaccine in Europe, 7 April 2021
(2021-04-07)The Pan American Health Organization (PAHO) has issued this communiqué in response to the information circulating about potential risks associated with use of the COVID-19 vaccine developed by AstraZeneca and Oxford ... -
Establishment and Validation of a Pseudovirus Neutralization Assay for SARS-CoV-2
(2020-03-24)Pseudoviruses are useful virological tools because of their safety and versatility, especially for emerging and re-emerging viruses. Due to its high pathogenicity and infectivity and the lack of effective vaccines and ... -
Interim guidance on continuity of immunization programs during the COVID-19 pandemic
(2020-05-13)Preamble: As a public health emergency of international concern, the coronavirus disease 2019 (COVID-19) pandemic (caused by the novel SARS-CoV-2 virus) has already impacted many aspects of healthcare delivery. Within ... -
An international randomised trial of candidate vaccines against COVID-19
(2020-04-09)Summary: Recognizing the critical importance to world health of the rapid availability and deployment of effective vaccines against COVID-19, this large, international, multi-site, individually randomized controlled clinical ... -
No evidence supports the use of ether and chloroform inhalation for treating COVID-19
(2020-03)Dear Editor, SARS-CoV-2 has been spreading rapidly across the world as well as the number of fake news on social media regarding harmful or non-harmful treatments which are ineffective for treating COVID-19. In Brazil, the ... -
Programas de inmunización a medida (PIM)
(2020-04-27)La vacunación o inmunización es una excelente intervención de salud, que salva millones de vidas y ahorra aún más dolor y sufrimiento. Permite reducir las desigualdades, aumentar el acceso a los servicios de salud en general ... -
Reverse vaccinology approach to design a novel multi-epitope vaccine candidate against COVID-19: an in silico study
(2020-04-15)At present, novel Coronavirus (2019-nCoV, the causative agent of COVID-19) has caused worldwide social and economic disruption. The disturbing statistics of this infection promoted us to develop an effective vaccine candidate ... -
A Review of SARS-CoV-2 and the Ongoing Clinical Trials
(2020-04-10)The sudden outbreak of 2019 novel coronavirus (2019-nCoV, later named SARS-CoV-2) in Wuhan, China, which rapidly grew into a global pandemic, marked the third introduction of a virulent coronavirus into the human society, ... -
The SARS-CoV-2 Vaccine Pipeline: an Overview
(2020-03-03)Purpose of Review: The goal of this review is to provide a timely overview on efforts to develop a vaccine for the 2019 novel coronavirus SARS-CoV-2, the causative agent of coronavirus disease (COVID-19). Recent Findings: ... -
Social network-based distancing strategies to flatten the COVID-19 curve in a post-lockdown world
(2020-06-04)Social distancing and isolation have been widely introduced to counter the COVID-19 pandemic. Adverse social, psychological and economic consequences of a complete or near-complete lockdown demand the development of more ... -
Structure of the RNA-dependent RNA polymerase from COVID-19 virus
(2020-04-10)A novel coronavirus (COVID-19 virus) outbreak has caused a global pandemic resulting in tens of thousands of infections and thousands of deaths worldwide. The RNA-dependent RNA polymerase (RdRp, also named nsp12) is the ... -
The use of renin angiotensin system inhibitor on mortality in patients with coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis
(2020-06-27)Background and Aims: To investigate the association between use of angiotensin-converting enzyme inhibitor (ACEI)/angiotensin-receptor blocker (ARB) and outcomes of hypertensive COVID-19 patients, a systematic review and ...