Serological survey for the prevalence of certain arboviruses in the human population of the south-east area of Central African Republic (author's transl)

Abstract

A serological survey of antibodies to arboviruses was carried out in the human population of the south-east part of Central African Republic in April 1979. Four hundred and fifty nine serum samples were tested using the haemagglutination inhibition test (H. I.) and fifty of them by the complement fixation test (C. F.). Only 11% of the population tested had no H. I. antibodies against the following arboviruses: Chikungunya, Semliki-forest, Sindbis, Yellow fever, Uganda S, West-Nile, Zika, Bunyamwera and Zinga. It seems that Chikungunya virus has recently been very active mainly in adult population. The same observation was reported for Zika virus. The following antigens were used for complement fixation test: Ilesha, Bwamba, CHF-Congo, Dugbe, Bhanja, Tataguine, Nyando, Bangui and Orungo. A positive reaction was noted in 88% of serum samples tested for Orungo virus. Antibodies were also detected by CF for CHF-Congo and Bhanja viruses.