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dc.contributor.authorMonath, T P
dc.contributor.authorSchlesinger, J J
dc.contributor.authorBrandriss, M W
dc.contributor.authoret al.
dc.description.abstractMonoclonal antibodies directed against the envelope glycoprotein and the NV3 non-structural viral protein of yellow fever (YF) were tested by the indirect fluorescent antibody technique against a variety of YF virus strains and heterologous flaviviruses. Monoclonal antibodies directed against the envelope glycoprotein exhibited YF strain-specificity, YF type-specificity, broad group cross-reactivity, or limited subgroup reactivity (YF + Banzi or YF + Koutango + Zika + Usutu + Uganda S). Monoclonal antibodies directed against NV3 reacted either with YF + Koutango or with YF + Banzi. These findings generally correlated with the results of biological tests reported previously. Monoclonal antibodies that were type-specific to YF will be useful for the rapid specific identification of YF virus isolates and are available from the Centers for Disease Control on request.en_US
dc.subjectZika Research Projecten_US
dc.subjectZika Virusen_US
dc.subjectYellow Feveren_US
dc.subjectMonoclonal Antibodiesen_US
dc.titleYellow fever monoclonal antibodies: type-specific and cross-reactive determinants identified by immunofluorescenceen_US
eihealth.categoryEpidemiology and epidemiological studiesen_US
eihealth.typeResearch protocol informationen_US
eihealth.maincategorySave Lives / Salvar Vidasen_US
dc.relation.ispartofjournalAmerican Journal of Tropical Medicine and Hygieneen_US

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