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Applying Wolbachia to Eliminate Dengue AWED
dc.contributor.author | Utarini, Adi | |
dc.contributor.author | Ahmad, Riris A | |
dc.contributor.author | Indriani, Citra | |
dc.date.accessioned | 2021-07-22T19:14:23Z | |
dc.date.available | 2021-07-22T19:14:23Z | |
dc.date.issued | 2017 | |
dc.identifier.uri | https://clinicaltrials.gov/ct2/show/NCT03055585 | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.12663/2628 | |
dc.description.abstract | This cluster randomised trial will evaluate the efficacy of Wolbachia-infected Aedes aegytpi mosquitoes in reducing dengue cases in Yogyakarta City, Indonesia. Primary objective: To assess the efficacy of community-based deployments of Wolbachia-infected Aedes aegypti mosquitoes in reducing the incidence of symptomatic, virologically-confirmed dengue cases of any severity in Yogyakarta residents aged 3-45 years in release areas, relative to non-release areas. Secondary objectives: To measure the efficacy of the Wolbachia method against each of the four DENV serotypes; to measure the efficacy of the Wolbachia method in reducing the incidence of symptomatic virologically confirmed Zika virus and chikungunya virus infection in release areas, relative to non-release areas; to quantify the level of human mobility within Yogyakarta City, and estimate the proportion of residents' exposure time that they spend outside the treatment arm to which they were randomised; and to determine whether community-based deployment of Wolbachia-infected Ae. aegypti mosquitoes reduces the abundance of wild-type Ae. aegypti adults, or alternatively, alters the abundance of adults from Aedes species other than Ae. aegypti (e.g. Ae. albopictus) | en_US |
dc.language | English | en_US |
dc.subject | Zika Research Project | en_US |
dc.subject | Aedes aegypti | en_US |
dc.subject | Chikungunya virus | en_US |
dc.subject | Dengue | en_US |
dc.subject | Wolbachia | en_US |
dc.subject | Zika Virus | en_US |
dc.subject | Indonesia | en_US |
dc.title | Applying Wolbachia to Eliminate Dengue AWED | en_US |
eihealth.country | Others | en_US |
eihealth.category | Epidemiology and epidemiological studies | en_US |
eihealth.type | Other publications | en_US |
eihealth.maincategory | Protect Health Care Workers / Proteger la Salud de los Trabajadores | en_US |
dc.relation.ispartofjournal | Clinical Trials | en_US |
dc.contributor.corporatename | Indonesia. Faculty of Medicine, Universitas Gadjah Mada | en_US |
dc.contributor.corporatename | Australia. Monash University | en_US |
dc.contributor.corporatename | Indonesia. The Tahija Foundation | en_US |
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