Rapid Review Update 3: What is known on the potential for COVID-19 re-infection, including new transmission after recovery?

Abstract

Background: The potential for COVID-19 re-infection is an important public health issue, as potential for re- infection will significantly impact future infection prevention and control measures, particularly related to vaccine development and immunization efforts. This rapid review was produced to support public health decision makers’ response to the coronavirus disease (COVID-19) pandemic. This review seeks to identify, appraise, and summarize emerging research evidence to support evidence-informed decision making. This rapid review is based on the most recent research evidence available at the time of release. A previous version was completed on August 27, 2020. This version includes evidence available up to September 18, 2020. In this rapid review, we provide the most recent research evidence to answer the question: what is known on the potential for COVID-19 re-infection, including new transmission after recovery? What has changed in this version? • Four low and moderate quality syntheses were added to this version, along with one high quality cohort study.