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Stroke and Novel Coronavirus Infection in Humans: A Systematic Review and Meta-Analysis
(2020-10-06)Background: As the world witnessed the devastation caused by the coronavirus disease 2019 (COVID-19) outbreak, a growing body of literature on COVID-19 is also becoming increasingly available. Stroke has increasingly been ... -
Strong associations and moderate predictive value of early symptoms for SARS-CoV-2 test positivity among healthcare workers, the Netherlands, March 2020
(2020-04-03)Healthcare workers (n = 803) with mild symptoms were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (n = 90 positive) and asked to complete a symptom questionnaire. Anosmia, muscle ache, ocular ... -
Structural and biochemical characterization of SADS‐CoV papain‐like protease 2
(2020-03)Swine acute diarrhea syndrome coronavirus (SADS‐CoV) is a novel coronavirus that is involved in severe diarrhea disease in piglets, causing considerable agricultural and economic loss in China. The emergence of this new ... -
Structural Genomics of SARS-CoV-2 Indicates Evolutionary Conserved Functional Regions of Viral Proteins
(2020-03-25)During its first two and a half months, the recently emerged 2019 novel coronavirus, SARS-CoV-2, has already infected over one-hundred thousand people worldwide and has taken more than four thousand lives. However, the ... -
Structure of the RNA-dependent RNA polymerase from COVID-19 virus
(2020-04-10)A novel coronavirus (COVID-19 virus) outbreak has caused a global pandemic resulting in tens of thousands of infections and thousands of deaths worldwide. The RNA-dependent RNA polymerase (RdRp, also named nsp12) is the ... -
Structure of the thermally stable Zika virus
(2016-06)Zika virus (ZIKV), formerly a neglected pathogen, has recently been associated with microcephaly in fetuses1, and with Guillian–Barré syndrome in adults2. Here we present the 3.7 Å resolution cryo-electron microscopy ... -
Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody
(2016-06)Zika virus (ZIKV), a mosquito-borne flavivirus, is a current global public health concern. The flavivirus envelope (E) glycoprotein is responsible for virus entry and represents a major target of neutralizing antibodies ... -
Study of INTERCEPT Blood System for Red Blood Cells in Regions at Potential Risk for Zika Virus Transfusion-Transmitted Infections (RedeS) RedeS
(2017)Stage A: To evaluate the safety and efficacy of the INTERCEPT Blood System for Red Blood Cells Pathogen Reduction Treatment (PRT) in comparison to conventional RBCs in adult patients who require RBC transfusion support. Stage ... -
Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2)
(2020-03-16)Estimation of the prevalence and contagiousness of undocumented novel coronavirus (SARS-CoV2) infections is critical for understanding the overall prevalence and pandemic potential of this disease. Here we use observations ... -
Successful containment of COVID-19: the WHO-Report on the COVID-19 outbreak in China
(2020-03-17)SARS-CoV-2 is a new Coronavirus, with first infections detected in humans late in 2019. The emergence of SARS-CoV-2 has led to a large outbreak in China and is currently causing outbreaks in many countries. The disease ... -
Suggestions for thromboprophylaxis and laboratory monitoring for in-hospital patients with COVID-19
(2020-04-11)Growing evidence from multiple retrospective cohorts indicates that hospitalised COVID-19 patients often could suffer from an excessive coagulation activation leading to an increased risk of venous and arterial thrombosis ... -
Suggestions on the prevention of COVID-19 for health care workers in department of otorhinolaryngology head and neck surgery
(2020-04-02)The epidemic of the Coronavirus Disease 2019 (COVID-19) has presented as a grim and complex situation recently. More than 77,000 cases of COVID-19 has been confirmed in China until February 25th, 2020, which are causing ... -
Suicide during COVID-19 and other major international respiratory outbreaks: A systematic review
(2020-12-26)Coronavirus disease 2019 (COVID-19) was recently declared a pandemic by the WHO. This outbreak threatens not only physical health but also has significant repercussions on mental health. In recent world history, major ... -
Sumário de resumos sobre vitamina D e infecções por Sars-CoV-2: qual a relação entre a hipovitaminose ou a suplementação de vitaminas D as infecções por SARS-COV-2? (09 de abril de 2020)
(2020-04-09)Objetivos: avaliar a eficácia da suplementação de vitamina D na prevenção de infecções por SARS-CoV-2 e a associação entre deficiência de vitamina D e risco de infecções por SARS-CoV-2. -
Summary on Advances in the Development of Vaccines against COVID-19, 3 April 2020
(2020-06-03)This document presents a brief summary of vaccines in development for COVID-19. At the end of 2019, the new SARS-CoV-2 coronavirus emerged. Although there is not yet a vaccine against this virus, the field of research for ... -
Supply & markets working group notes for the record 29 May, 11 June 2020
(2020-06-11)Action points: • WHO to share bilaterally the template for aggregated requests with interested organizations. Updates: • Requests for essential items for a total value of USD 90M are registered in the Supply Portal. • WHO ...