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Now showing items 2460-2479 of 2964
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Reverse vaccinology approach to design a novel multi-epitope vaccine candidate against COVID-19: an in silico study
(2020-04-15)At present, novel Coronavirus (2019-nCoV, the causative agent of COVID-19) has caused worldwide social and economic disruption. The disturbing statistics of this infection promoted us to develop an effective vaccine candidate ... -
Review of Current Evidence of Hydroxychloroquine in Pharmacotherapy of COVID-19
(2020-05-13)Importance: The COVID-19 Pandemic has literally left the world breathless in the chase for pharmacotherapy. With vaccine and novel drug development in early clinical trials, repurposing of existing drugs takes the center ... -
A Review of SARS-CoV-2 and the Ongoing Clinical Trials
(2020-04-10)The sudden outbreak of 2019 novel coronavirus (2019-nCoV, later named SARS-CoV-2) in Wuhan, China, which rapidly grew into a global pandemic, marked the third introduction of a virulent coronavirus into the human society, ... -
Revisão das alterações neurorradiológicas em exames de TC e RM realizados em crianças nascidas entre 2015 e 2016, durante a epidemia de Zika vírus, em comparação ao ano de 2014, nos estados de Pernambuco e Paraíba, Brasil
(2016)A fonte original deste documento pode ser restrita, impedindo o acesso de leitores externos ao conteúdo, ou não estar mais disponível. Sendo assim, os usuários precisam utilizar outros recursos para recuperar essas informações. -
Revisão sistemática rápida sobre atividade viral de coronavírus humano em superfícies domésticas e hospitalares: qual é a atividade viral de MERS-CoV, SARS-CoV E SARS-CoV-2 em superfícies domésticas e hospitalares? (06 de maio de 2020)
(2020-05-06)Objetivos: Reunir e analisar as evidências científicas existentes sobre a atuação do coronavírus humano (MERS-CoV, SARS-CoV e SARS-CoV-2) para estimar a duração da sua atividade viral e avaliar a manutenção da virulência ... -
Revisão sistemática rápida sobre eficácia e segurança de plasma convalescente para tratamento de infecções por Sars-CoV-2: o uso de plasma convalescente é eficaz e seguro para tratar infecções por SARS-COV-2 (COVID-19)? (13 de abril de 2020)
(2020-04-13)Objetivos: Identificar e avaliar evidências científicas acerca da eficácia e segurança de plasma convalescente para tratamento de infecções por SARS-CoV-2. -
Revisão sistemática rápida sobre resposta imunológica e reinfecção por SARS-CoV-2: qual é a resposta imunológica de pacientes considerados curados de COVID-19? Há evidências de reinfecção? (03 de abril de 2020)
(2020-04-03)Objetivos: Identificar evidências científicas sobre resposta imunológica e reinfecção por SARS-CoV-2 (COVID-19), para responder às seguintes perguntas: 1. Há evidências de que a carga viral de SARS-CoV-2 possa variar/aumentar ... -
Revision to CDC’s Zika Travel Notices: Minimal Likelihood for Mosquito-Borne Zika Virus Transmission at Elevations Above 2,000 Meters
(2016-06)Since May 2015, when Zika virus, a flavivirus transmitted primarily by Aedes aegypti mosquitoes, was reported in Brazil, the virus has rapidly spread across the Region of the Americas and the Caribbean. The association ... -
A rhesus macaque model of Asian-lineage Zika virus infection
(2016-06)Infection with Asian-lineage Zika virus (ZIKV) has been associated with Guillain–Barré syndrome and fetal abnormalities, but the underlying mechanisms remain poorly understood. Animal models of infection are thus urgently ... -
Ribavirin was beneficial for patients with SARS and MERS: uncertain if it is effective for patients with COVID-19
(2020-03-20)Citation: Luo T, Na Y, Tan L, et al. The Possibility of Ribavirin in the Treatment of the Coronavirus Disease 2019: A Systematic Review. China Pharmaceuticals 2020; 29(5): 34-9 Language: Chinese What is this? Like COVID-19, ... -
Risk assessment for yellow fever in western and North-Western provinces of Zambia
(2015)Background: North-Western and Western provinces of Zambia were reclassified as low-risk areas for yellow fever (YF). However, the current potential for YF transmission in these areas is unclear. Aims: To determine the ... -
Risk estimation of the SARS-CoV-2 acute respiratory disease outbreak outside China
(2020-06-05)Background: On December 31, 2019, the World Health Organization was alerted to the occurrence of cases of pneumonia in Wuhan, Hubei Province, China, that were caused by an unknown virus, which was later identified as a ... -
Risk factors and prognosis for COVID-19-induced acute kidney injury: a meta-analysis
(2020-11-10)Objective: To analyse the incidence, risk factors and impact of acute kidney injury (AKI) on the prognosis of patients with COVID-19. Design: Meta-analysis. Data sources: PubMed, Embase, CNKI and MedRxiv of Systematic ... -
Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan
(2020)Background: In December 2019, the coronavirus disease 2019 (COVID-19) outbreak occurred in Wuhan. Data on the clinical characteristics and outcomes of patients with severe COVID-19 are limited. Objective: We sought to ... -
Risk factors of COVID-19 mortality: a systematic review of current literature and lessons from recent retracted articles
(2020-12-01)OBJECTIVE: Recently, two influential articles that reported the association of (hydroxy)chloroquine or angiotensin converting enzyme (ACE) inhibitors and coronavirus disease 2019 (COVID-19) mortality were retracted due to ... -
Risk Factors of Healthcare Workers with Corona Virus Disease 2019: A Retrospective Cohort Study in a Designated Hospital of Wuhan in China
(2020-03-17)Corona Virus Disease 2019 (COVID-19) originated in Wuhan, China has caused many healthcare workers (HCWs) infected. Seventy-two HCWs manifested with acute respiratory illness were retrospectively enrolled to analyze the ... -
Risk mitigation tool for child and youth settings operating during the COVID-19 pandemic
(2020-06-01)Objective: This tool will assist school boards and operators of child and youth settings in considering risks to children/youth, staff and volunteers during the coronavirus disease (COVID-19) pandemic, and provide examples ... -
Risk mitigation tool for gatherings and events operating during the COVID-19 pandemic
(2020-06-19)Objective: This tool will assist individuals, groups, or organizations, representing diverse groups based on gender, ethnicity/culture, and other socio-economic and demographic factors, in considering risks related to ... -
Risk mitigation tool for outdoor recreation spaces and activities operating during the COVID-19 pandemic
(2020-06-26)Objective: This tool will assist in considering risks associated with the use of parks and outdoor recreational spaces during the coronavirus disease (COVID-19) pandemic and provide examples of strategies that may be ...