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N-acetylcysteine: A rapid review of the evidence for effectiveness in treating COVID-19
(2020-04-14)An old drug repurposed? N-acetylcysteine (NAC) was introduced in the 1960s as a mucolytic drug for chronic respiratory diseases. It has a well-established safety profile and is still commonly used orally at doses of 600mg/day ... -
Narrative synthesis of psychological and coping responses towards emerging infectious disease outbreaks in the general population: practical considerations for the COVID-19 pandemic
(2020-04-03)[Abstract]. Introduction: Emerging infectious disease outbreaks, such as the present coronavirus disease 2019 (COVID-19) pandemic, often have a psychological impact on the well-being of the general population, including ... -
National capacities review tool for a novelcoronavirus
The main aim of the national capacities review tool is to better understand existing capacities in the area of detection and response to a novel coronavirus (nCoV) that is zoonotic and causes respiratory disease. The tool ... -
National Institute for the Infectious Diseases “L. Spallanzani” IRCCS. Recommendations for COVID-19 Clinical Management
(2020-03-16)On January 9th, 2020, the “World Health Organization” (WHO) declared the identification, by Chinese Health authorities, of a novel coronavirus, further classified as SARS-CoV-2 responsible of a diseases (COVID-19) ranging ... -
National Response to COVID-19 in the Republic of Korea and Lessons Learned for Other Countries
(2020-04-29)In the first two months of the COVID-19 pandemic, the Republic of Korea (South Korea) had the second highest number of cases globally yet was able to dramatically lower the incidence of new cases and sustain a low mortality ... -
The Natural History of Severe Acute Respiratory Syndrome Coronavirus 2–Related Multisystem Inflammatory Syndrome in Children: A Systematic Review
(2020-09-14)Background: The clinical manifestations and natural history of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–related multisystem inflammatory syndrome in children (MIS-C) are poorly defined. Using a systematic ... -
Nervous system involvement after infection with COVID-19 and other coronaviruses
(2020-03-30)Viral infections have detrimental impacts on neurological functions, and even to cause severe neurological damage. Very recently, coronaviruses (CoV), especially severe acute respiratory syndrome CoV 2 (SARS-CoV-2), exhibit ... -
Neuraxial anaesthesia and peripheral nerve blocks during the COVID‐19 pandemic: a literature review and practice recommendations
(2020-04-28)Coronavirus disease 2019 (COVID‐19) has had a significant impact on global healthcare services. In an attempt to limit the spread of infection and to preserve healthcare resources, one commonly used strategy has been to ... -
Neuro-oncology Management During the COVID-19 Pandemic With a Focus on WHO Grade III and IV Gliomas
(2020-05-05)Background: Because of the increased risk in cancer patients of developing complications caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), physicians have to balance the competing risks of the ... -
Neurodesenvolvimento e neuroimagens de crianças sem microcefalia nascidas de gestantes com infecção pelo vírus Zika - estudo de coorte
(2016)A fonte original deste documento pode ser restrita, impedindo o acesso de leitores externos ao conteúdo, ou não estar mais disponível. Sendo assim, os usuários precisam utilizar outros recursos para recuperar essas informações. -
Neurodevelopment Outcome of Newborns Exposed to Zika Virus (ZIKV) in Utero ZEN Iniciative
(2016)This prospective cohort study will determine the natural history of fetal exposure to Zika virus (ZIKV) and its effects on the fetus and newborn with emphasis on neurodevelopment outcome. Exposure of the fetus will be ... -
Neuroimaging findings of brain MRI and CT in patients with COVID-19: A systematic review and meta-analysis
(2020-11-02)Purpose: To comprehensively evaluate the incidences of abnormal neuroimaging findings in patients with COVID-19 via a systematic review and meta-analysis. Method: PubMed-MEDLINE and EMBASE were searched for original articles ... -
Neurologic manifestations of arboviruses in the epidemy of pernambuco, Brazil
(2016-07)INTRODUCTION Dengue has affected Rio de Janeiro City since the 1980s. The sequential Zika and chikungunya virus introductions during 2015 aggravated the health scenario, with 97,241 cases of arboviral diseases reported ... -
Neurological associations of COVID-19
(2020-07-02)Background: The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is of a scale not seen since the 1918 influenza pandemic. Although the predominant clinical presentation is with ... -
Neurological Involvement in COVID-19 Patients: A Narrative Review
(2020-09-04)Background: Coronavirus disease 2019 (COVID-19) is a viral disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) belonging to the coronavirus family. The primary target of SARS-CoV-2 is peripheral ... -
Neutralizing Antibodies Responses to SARS-CoV-2 in COVID-19 Inpatients and Convalescent Patients
(2020-04-23)Background. COVID-19 is a pandemic with no specific antiviral treatments or vaccines. The urgent needs for exploring the neutralizing antibodies from patients with different clinical characteristics are emerging. Methods. ... -
Neutrophil calprotectin identifies severe pulmonary disease in COVID-19
(2020-05-10)Severe cases of coronavirus disease 2019 (COVID-19) are regularly complicated by respiratory failure. While it has been suggested that elevated levels of blood neutrophils associate with worsening oxygenation in COVID-19, ... -
Neutrophil-to-lymphocyte ratio as an independent risk factor for mortality in hospitalized patients with COVID-19
(2020-04-03)[Abstract]. Background: Several studies have described the clinical characteristics of patients with novel coronavirus (SARS-CoV-2)-infected pneumonia (COVID-19), indicating severe patients tended to have higher neutrophil ... -
Neutrophil‐to‐lymphocyte ratio and lymphocyte‐to‐C‐reactive protein ratio in patients with severe coronavirus disease 2019 (COVID‐19): A meta‐analysis
(2020-04-03)To the Editor, Since March 11, 2020, the World Health Organization defined coronavirus disease 2019 (COVID‐19) as a pandemic, with a series of confirmed cases that currently exceeded 300,000 people worldwide and with ...